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Archive for the ‘science and medicine’ Category

Relieving chronic pain

Posted by Charles II on September 10, 2015

I suggest listening to the following presentation by Daniel Clauw, U. Michigan Medical:

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Taking any generics?

Posted by Charles II on September 10, 2015

Amy Kazmin, FT:

Indian companies manufacture a lot of the generic drugs we use–30 to 40% of what we use in the US.

They don’t manufacture them very well. The EU has banned 700 of them. The US has banned 39 companies from exporting to the US. A Japanese company bought Ranbaxy… and promptly wrote down the investment by nearly the purchase price.

And, of course, one of the worst of them, Emcure, is owned by Bain Capital.

So, good luck if you rely on any generics! The free market is taking care of everything!

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Media reports to the contrary, global warming is still on

Posted by Charles II on July 15, 2015

Jim Wild, Lancaster University:

Recent headlines are warning that the Earth will enter into a “mini ice age” in about 20 years because the sun is heading towards a period of very low output. Here’s why this scenario is extremely unlikely.

So what about global climate change? If solar activity is falling, and that has a cooling influence over the UK and Europe, isn’t that a good thing?

Unfortunately not. The overwhelming consensus among the world’s climate scientists is that the influence of solar variability on the climate is dwarfed by the impact of increased levels of carbon dioxide in the atmosphere. Most calculations suggest that a new “grand solar minimum” in activity would have a cooling effect that would temporarily offset just a few year’s worth of the warming due to the emission of carbon dioxide by humans.

We may well be heading towards a period of low solar activity, but a new mini ice age seems very unlikely at this point.

Briefly, the last Little Ice Age was probably due more to volcanic activity than to fluctuations in solar output.

Expressing my outrage with those who twist scientific work into support for the petroleum industry’s profits is impossible without swearing.

For that matter, suppose we are going to have a Mini Ice Age. Shouldn’t we should be saving fossil fuels for when we’ll need them? But for hypocrites, there are no boundaries, no reason, nothing except their narcissistic pursuit of planetary destruction.

Posted in environment, global warming, liars, science and medicine | 1 Comment »

Light on your feet …and, farm gushers

Posted by Charles II on June 16, 2015

Anmar Frangoul, CNBC:

Pavegen is a London-based company that is looking to harvest the energy from our footsteps to do precisely this. They have designed and built flooring that converts the kinetic energy we produce when walking into clean, renewable electricity.

“The Pavegen panels convert the weight of your footsteps into electricity, so every time you walk on our product it harnesses a small amount of energy from every single step,” Laurence Kemball-Cook, CEO and Founder of Pavegen, told in a phone interview.

Anmar Frangoul, CNBC:

The global chemical industry is vast, and has an environmental impact to match. According to a 2013 report by International Energy Agency, the chemical and petrochemical sector accounts for approximately seven percent of the world’s greenhouse gas emissions.

One Illinois-based company is working to change an industry which has traditionally relied on oil-based products.

Elevance Renewable Sciences have developed technology and a process that they say enables them to “successfully bridge the renewables and chemicals industries, transforming natural plant-based oils… into speciality high-performance, cost-effective commercial products.”

Posted in energy, environment, science and medicine | 3 Comments »

First, do no harm

Posted by Charles II on February 25, 2015

Gregg Levine, Al-Jazeera:

Perhaps it will not come as a big surprise to learn that the highly trafficked, for-profit medical information site WebMD keeps track of your search terms and then makes some of the information available to third-party vendors. It’s kind of like what the term “for profit” means. But how about one of the other top hits for health-related searches, the Centers for Disease Control? That’s a non-profit government agency — they don’t provide information to marketing interests, right?


Just the thing we want for people who have medical conditions which may endanger the rest of us– a reason to fear that their privacy will be compromised. What is wrong with the CDC (not to mention Mayo and other for-profit sites of institutions that pretend to be engaged in the practice of medicine)?

Posted in abuse of power, science and medicine | 1 Comment »

Good news on the anti-bug front

Posted by Charles II on October 10, 2013

This news is a little old, but I hadn’t heard it. David Heitz, Healthline:

A blood test developed by researchers at Duke University can predict with tremendous accuracy whether someone with, say, pneumonia has a viral or bacterial infection, even if it’s a previously unknown strain.

The test, described today in the journal Science Translational Medicine, could someday help stop the unnecessary prescribing of antibiotics to patients who have viral infections.

In the most recent experiment, 102 subjects with viral and bacterial infections, as well as healthy control patients, arrived at a hospital emergency room and were given the blood test. With about 90 percent accuracy, the test returned the proper diagnosis in just 12 hours.

In larger studies set to begin as early as this flu season, scientists will look at ways of paring down the number of genes the test analyzes and reducing the test’s turnaround time to as little as one hour.

Posted in Good Things, science and medicine | 2 Comments »

Vote for your favorite science cartoon

Posted by Charles II on May 17, 2013

UCS has sponsored a competition here.

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The de-leading of America

Posted by Charles II on January 3, 2013

Via Atrios, an article by Kevin Drum, MoJo.

The key takeaway:

A followup is here.

Posted in crimes, environment, science and medicine | 9 Comments »

The need for regulation

Posted by Charles II on December 23, 2012

Kathleen McLaughlin, The Guardian:

International health experts are warning of a mounting health crisis in parts of Africa because of an influx of counterfeit medicine from Asia that is playing havoc with the treatment of diseases such as malaria. Porous borders in Africa coupled with indifferent oversight in China are combining to turn the continent and its pressing health problems into a free-for-all for maverick manufacturers, some of whom are producing pills with no active ingredients at all.

Patrick Lukulay, vice president of the US Pharmacopeial Convention’s global health impact programmes, said it was no secret that the majority of dangerous medications came from China and India, as those countries had the world’s largest production bases for both active ingredients and finished drugs.

While India has stepped up oversight, “China is only now just catching on”, he added.

And more from McLaughlin:

There are fake malaria drugs, antibiotics and even emergency contraceptives. This in a country battling the world’s third highest birthrate, with five to six children per woman keeping the population mired in poverty. Some pills contain no active ingredients, some are partial strength and some the wrong formulation entirely.

“Let’s not exonerate other countries, by the way,” he added, noting that African factories had also been busted for making fakes.

I wish that I could say that the US is not headed in the same direction, but ever since the 1980s, quality standards have been under attack. Not all that long ago, I had a run-in with a flu vaccine that should have been impossible. And, while problems as egregious as those reported by McLaughlin are still rare in the US, other kinds of corner-cutting are common, as evidenced by the many scandals showing substandard clinical testing.

Posted in crimes, science and medicine | 1 Comment »

Obesity: the brain chemistry behind fat

Posted by Charles II on December 5, 2012

A remarkable series of articles on brain chemistry and obesity has been opened to the public by the New York Academy of Sciences.

Kaiser et al. (U. Alabama) give an overview on a hypothesis that, given a perceived deficiency in food availability, the body either adds fat or slows metabolism in a way that lengthens life, depending on whether calories are actually available.

William Banks, VA looks at the role of leptin, a protein that diminishes the desire to eat. In obese people, leptin is, paradoxically, overabundant. This represents a resistance syndrome analogous to insulin resistance. One of the regulators of leptin transport into the brain is triglyceride. In starvation, triglyceride levels rise. Short term fasting increases facilitates leptin transport into the brain, but long-term fasting does the opposite. So fasting can play a positive role in helping to reduce hunger.

Renato Pasquali of Malpighi Hospital in Bologna looks at stress hormones and sex hormones: “stress activates the hypothalamic–pituitary–adrenal (HPA) axis, the sympathetic nervous system (SNS), and the sympathoadrenal system” resulting in the rise of cortisol and catecholamines and an activation of blood pressure elevators like renin and its target, angiotensin. During chronic stress, cortisol elevates lipoprotein lipase, which stores fat especially in the abdomen (perhaps that explains the apple/pear dichotomy, with people with waist fat suffering greater health effects). The term allostatic load refers to the damage inflicted by adapting to adversity. In women, abdominal fat seems to be related to a rise in androgens (male hormones), while in men, to female hormones.

Lucassen et al (NIH and elsewhere) look at the relationship of sleep to obesity. Sleep has declined by over 1.5hr over the last 50 years. Slow wave sleep, which diminishes with age, is probably especially important, though it’s still not clear what’s correlation and what’s causation.

There’s plenty more here.

Posted in health issues, science and medicine | Comments Off on Obesity: the brain chemistry behind fat

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